Take Life Science AI from
Copilot to Autopilot.
The agentic operating system for R&D. Orchestrate dry lab computations and wet lab automation with precision-engineered autonomous agents.
From hypothesis to discovery in hours.
Legacy pipelines take weeks to configure and run. SigmaticeOS agents dynamically construct pipelines on the fly, dramatically accelerating the path to clinical value.
One platform. Every layer of the discovery loop.
From the orchestration of autonomous agents to embedded experiences in your team's existing tools — SigmaticeOS unifies the work of every scientist on the bench and at the keyboard.
Autonomous agents,
orchestrated as one mesh
Scout decomposes every research question into specialized sub-agents — docking, ADMET, literature, assay design — and runs them in parallel orbit, converging on a single auditable finding.
Embed Scout into the tools
your scientists already use
Drop the SigmaticeOS SDK into Benchling, your internal ELN/LIMS, Jupyter, or a custom portal — Scout shows up where the science already happens, with full audit trails attached.
How Scout works.
Provide a hypothesis in plain language. Scout translates intent into action, orchestrating hundreds of tools to validate findings.
1. Hypothesis
Scientists submit natural language queries (e.g. 'Analyze binding affinity for KRAS mutants')
2. Agent Selection
Scout decomposes the task and provisions specialized sub-agents
3. Parallel Analyses
Agents orchestrate docking, ADMET prediction, and literature review simultaneously
4. Cross-Validation
Results are continuously cross-referenced against your proprietary ELN/LIMS data
5. Auditable Finding
A deterministic, fully traceable report is generated with zero hallucination
The Agentic Stack.
SigmaticeOS is built from the ground up for the complexities of modern biology. We separate reasoning from execution, ensuring every action is deterministic and verifiable.
Audit & Compliance Plane
Cryptographic logging of all inputs, prompts, and outputs for 21 CFR Part 11 readiness.
Orchestration Layer
The cognitive engine. Scout manages context windows, planning, and task delegation.
Agent Fabric
Specialized domain agents (Cheminformatics, Genomics, Literature) operating in parallel.
Tool & Data Integration
Native API hooks into a growing catalogue of scientific software and your proprietary databases.
Wet Lab Interface
Direct command translation for liquid handlers and automated testing suites.
Designed to integrate the tools scientists already use
SigmaticeOS is built to talk to the industry-standard software that powers modern R&D — from cheminformatics to lab automation.
Wet lab, meet dry lab.
Stop manually writing scripts for liquid handlers. SigmaticeOS translates computational experimental designs directly into executable protocols for your laboratory instrumentation.
Use cases across the pipeline.
From early discovery to clinical biomarkers, configure agents for your specific scientific domain.
Target Discovery
Mine vast multi-omics datasets and literature concurrently to identify and rank novel therapeutic targets with cryptographically auditable rationale.
Lead Optimization
Automate docking, molecular dynamics, and generative chemistry cycles to rapidly evolve hit compounds into viable leads.
Assay Design & Analysis
Agents automatically design CRISPR guides, construct plasmids, and analyze flow cytometry results returning structured insights.
ADMET Prediction
Run parallel in-silico toxicity and pharmacokinetic screens before committing resources to physical synthesis.
Translational Research
Bridge preclinical animal models to human clinical data, identifying translatable signatures faster.
Clinical Biomarker Mining
Ingest unstructured clinical trial notes and patient data to extract potential response biomarkers.
Built for regulated science.
AI without traceability is useless in pharma. SigmaticeOS provides a cryptographically secure audit trail for every action, meeting the strictest industry standards.
Security and Sovereignty by Design
Your IP never leaves your control boundary.
(LIMS/ELN)
Execution
Built on AWS.
SigmaticeOS deploys into your own AWS account or a dedicated VPC we manage. We rely on AWS primitives — VPC isolation, IAM, KMS, Batch, S3 with encryption, and CloudTrail — so your security team can audit everything from day one.
Principles we're building on.
A new category of scientific software demands a new set of commitments to the people using it.
Provenance over plausibility
A finding without a reasoning trace is unusable in regulated science. Every agent action — every prompt, tool call, and intermediate result — is logged and reproducible.
Your data stays your data
We do not train on customer data. Workloads run in your VPC against open-weight models you control. There is no path for proprietary IP to leak into shared systems.
Tools first, language second
Agents are constrained to call deterministic scientific software (RDKit, BLAST, AlphaFold, etc.) rather than generate from parametric memory. The LLM plans; the tools answer.
Built with scientists, not for them
We work side-by-side with computational and bench scientists as design partners. The platform's roadmap is driven by real R&D bottlenecks, not by what's easy to demo.
Frequently Asked Questions
Ready to accelerate your pipeline?
Experience precision-engineered AI built specifically for the rigorous demands of life sciences R&D.